Letters ” Vitamin C research is not bad science”

January 20th, 2005 by Ben Goldacre in bad science | 3 Comments »

Vitamin C research is not bad science

Ben Goldacre describes one of my papers of a research study evaluating the anti-HIV action of vitamin C, and labels it as “bad science” as it was a laboratory study and it had nothing to do with AZT (Bad science, January 6). That is an unfortunate categorisation.

Laboratory studies are necessary prior to treating HIV in humans as they provide a rationale for clinical evaluation. It seems that the author was looking for a study comparing vitamin C with AZT and found an incorrect reference that evaluated only vitamin C. I should like to point out that subsequent to that first report, we published two successive papers that compared the anti-HIV effects of vitamin C to AZT. Both studies showed that whereas vitamin C suppressed HIV activation in latently or chronically-infected cells, AZT had no significant anti-HIV effect.

Our results on AZT were consistent with an independent report from another laboratory that also showed AZT to be ineffective in suppressing HIV expression in chronically-infected cells.

Simply because vitamin C has not been tested in humans, does not make vitamin C research a bad science. In fact, the reasons one would perform a clinical study are apparent in the above laboratory studies which have provided a compelling rationale for such testing. However, since vitamin C is a simple, inexpensive nutrient and not a drug with profit-generating potential, there has been little interest in testing it clinically. This is unfortunate as it keeps a potential non-toxic treatment from being further evaluated against a deadly life-threatening disease.
Raxit Jariwalla
California Institute for Medical Research, San Jose

[ Ben Goldacre responds here. ] or here

If you like what I do, and you want me to do more, you can: buy my books Bad Science and Bad Pharma, give them to your friends, put them on your reading list, employ me to do a talk, or tweet this article to your friends. Thanks! ++++++++++++++++++++++++++++++++++++++++++

3 Responses

  1. wokao123 said,

    October 15, 2009 at 8:14 am

    i like this article Links of London Links of London Links of London Links of London Tiffany Tiffany Tiffany Tiffany ED hardy ED hardy ED hardy UGG BOOTS UGG BOOTS UGG BOOTS UGG BOOTS

  2. wayscj said,

    November 21, 2009 at 8:26 am

    ed hardy ed hardy
    ed hardy clothing ed hardy clothing
    ed hardy shop ed hardy shop
    christian audigier christian audigier
    ed hardy cheap ed hardy cheap
    ed hardy outlet ed hardy outlet
    ed hardy sale ed hardy sale
    ed hardy store ed hardy store
    ed hardy mens ed hardy mens
    ed hardy womens ed hardy womens
    ed hardy kids ed hardy kids ed hardy kids

  3. Patrick Holford On Cell Studies and Antioxidants « Stuff And Nonsense said,

    August 19, 2010 at 9:51 pm

    [...] HIV-infected T-lymphocytic cell lines. This has been covered by  Ben Goldacre here (with follow-up here and [...]

You must be logged in to post a comment.