Oh, that was quick

November 21st, 2009 by Ben Goldacre in bad science, big pharma, regulating research | 61 Comments »

Ben Goldacre, Saturday 21 November 2009, The Guardian

Once your medicines regulator decides it should change the side effects warnings on the patient information of a drug taken by millions of people, how long do you think it would take for that change to be implemented?

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And now, nerd news

October 3rd, 2009 by Ben Goldacre in bad science, big pharma, hiding data, regulating research, systematic reviews, trial registers, vaccines | 34 Comments »

Ben Goldacre, Saturday 3 October 2009, The Guardian.

There are some very obvious problems that never seem to go away. Right now I can see 1,592 articles on Google News about one poor girl who died unexpectedly after receiving the cervical vaccine, and only 363 explaining that the post mortem found a massive and previously undiagnosed tumour in her chest. Meanwhile the Daily Mail this week continue their oncological ontology project with the magnificent headline: “Daily dose of housework could cut risk of breast cancer”.

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Pay to play?

February 14th, 2009 by Ben Goldacre in competing interests, MMR, regulating research | 46 Comments »

Ben Goldacre
Saturday February 14 2009
The Guardian

This column is about tainted medical research, not MMR. Now don’t get me wrong: it’s still an interesting week to be right about vaccines. On Sunday Read the rest of this entry »

Listen carefully, I shall say this only once

October 26th, 2008 by Ben Goldacre in academic publishing, badscience, big pharma, duplicate publication, regulating research | 17 Comments »

Ben Goldacre
The Guardian,
Saturday October 25 2008

Welcome to nerds’ corner, and yet another small print criticism of a trivial act of borderline dubiousness which will ultimately lead to distorted evidence, irrational decisions, and bad outcomes in what I like to call “the real world”.

So the ClinPsyc blog (clinpsyc.blogspot.com ) has spotted that the drug company Lilly have published identical data on duloxetine – a new-ish antidepressant drug – twice over, in two entirely separate scientific papers. Read the rest of this entry »

More crap journals?

October 4th, 2008 by Ben Goldacre in bad science, MMR, mondo academico, publication bias, regulating research, utter nonsense | 22 Comments »

Ben Goldacre
The Guardian
Saturday October 4 2008

Important and timely news from the Journal of Medical Hypotheses this week: ejaculating could be “a potential treatment of nasal congestion in mature males.” My reason for bothering you with this will become clear later. Read the rest of this entry »

Seriously. Is the Daily Mail any worse than your average academic journal?

September 20th, 2008 by Ben Goldacre in regulating research | 40 Comments »

As someone who is nerdishly fascinated by the systematic analysis of health risk data – check me out, ladies – I sometimes look at the health pages and try to work out what they’re supposed to do, what kind of information they offer, and for who.

This week, for example, you’ll have found: “Teenager helps his twin brother by donating a piece of his back“; “In pain? Take one Botticelli three times a day“; “Taking antibiotics to prevent premature birth can ‘increase risk’ of cerebral palsy“; Read the rest of this entry »

Pools of blood

May 10th, 2008 by Ben Goldacre in bad science, badscience, big pharma, regulating research, statistics | 14 Comments »

Note: The Guardian accidentally edited this column such that the last paragraph contained an untrue statement. I have emailed the readers editor for a correction.

Ben Goldacre
The Guardian,
Saturday May 10 2008

So basically I sit here with a big bag of standard tools from the world of evidence, and wait for stories to come along which allow me to deliver a 600 word lecture on them. Sit tight, this one’s slightly complicated. In America last week the papers went crazy: artificial blood products cause a 30% increase in deaths, and a 2.7-fold increase in heart attacks, according to a new meta-analysis in the Journal of the American Medical Association. There is, incidentally, a trial of these products still ongoing in the UK.

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Beau Funnel – updated with list of academic journals which actively encourage submission of negative results

March 8th, 2008 by Ben Goldacre in bad science, regulating research | 21 Comments »

Ben Goldacre
The Guardian,
Saturday March 8 2008

It was gratifying to see – after only a one-week delay – the government announcing that they would follow my suggestion on the comment pages last week, and demand that drug companies disclose all trial data, to make sure they’re not hiding anything. This has been pegged to the issue of undisclosed side-effects of antidepressants, because a drug company hiding side-effects is intuitively evil.

This is unfortunate because – as I have repeatedly argued – much more worrying is Read the rest of this entry »

UK Government does what I tell them – and – how would you write the legislation?

March 6th, 2008 by Ben Goldacre in regulating research | 19 Comments »

Just a brief post on how gratifying it is to see the government obediently doing exactly what I told them to and announcing plans to ensure that all drug company trial data is registered and disclosed. The MHRA press release is below so that you can bathe in unmediated news. Read the rest of this entry »

All bow before the might of the placebo effect, it is the coolest strangest thing in medicine

March 1st, 2008 by Ben Goldacre in homeopathy, placebo, regulating research | 31 Comments »

Ben Goldacre
The Guardian,
Saturday March 1 2008

It was fun to hear universal jubilation over the new meta-analysis showing once again that some antidepressants aren’t much cop in mild or moderate depression: most of all on the Today programme, where a newsreader said the industry was contesting the study on the basis that it was not in line “with patient experience”. I’ve always said that homeopaths mimic big pharma in their marketing spiel, but this is the first time I’ve seen it done the other way around, so bravo to pill peddlers of all shades. Read the rest of this entry »